Transcription activator-like effector nucleases (TALENs) are a type of gene editing technology that can be used to introduce specific changes into the DNA of living cells. TALENs are made by fusing a DNA-binding domain from a transcription activator-like effector (TALE) protein to a nuclease domain, an enzyme that can cut DNA. When a TALEN binds to a specific DNA sequence, the nuclease domain is activated and cuts the DNA at that location.
TALENs can be applied to help protect plants from the effects of climate change. TALENS have been used to improve the quality of products derived from crops.
This resource page provides news and research articles on TALENs published in Biotech Updates, as well as blogs, infographics, and publications developed by ISAAA, in partnership with The 2Blades Foundation.
- Experts Release Updates on TALEN Construction Systems (August 30, 2023)
- Enhanced Gene Editing in Ciona with CRISPR-Cas9 and TALENs (August 9, 2023)
- Scientists Create Gene-edited Allergen-free Chicken Eggs (May 24, 2023)
- Scientists Use TALENs to Edit Tuna (December 9, 2021)
- Japanese Researchers Develop New Gene-Editing Tool to Create Non-GM Crops (July 7, 2021)
- Researchers Explore Off-target Effects of TALEN-mediated Bar-knockout in Rice (May 5, 2021)
- New ISAAA Infographic Illustrates TALENs (March 10, 2021)
- TALEN Beats CRISPR-Cas9 in Editing Tightly-packed DNA (February 3, 2021)
- Researchers Report a Simple and Efficient TALE Using Twin Primer Assembly (January 27, 2021)
- TALENs Used for Multiple Gene Knockout in Chrysanthemum (November 4, 2020)
- Researchers Engineer a Rapid TALEN Assembly Protocol for Genome Editing (September 30, 2020)
- New Bicistronic TALENs Enhance Genome Editing (September 9, 2020)
- Scientists Use TALENs for Targeted Genome Editing of Potato (July 8, 2020)
- USDA Classifies Gene-Edited Soybean As Non-Regulated (June 10, 2020)
- Gene-Edited High-Fiber Wheat Could Hit the Market by 2020 (October 17, 2018)
- Researchers Test TALEN Genome Editing on Peanut (May 23, 2018)
- NDC80 Protein Complex Responsible for Cell Division in Arabidopsis (April 18, 2018)
- TALEN-Mediated Mutagenesis of Large Number of COMT Copies in Sugarcane (September 27, 2017)
- Evaluation of HvPAPhy_a Gene in Barley Using CRISPR-Cas9 and TALENs (August 9, 2017)
- TALEN-Mediated Knock-in Genome Editing in Silkworm (May 17, 2017)
- DNA Methylation Affects the Efficiency of TALEN-mediated Genome Editing in Rice (March 29, 2017)
- Programming Antiviral Defenses in Plants through Genome Editing (February 1, 2017)
- TALEN-mediated Mutagenesis of COMT in Sugarcane Improves Cell Wall Decomposition for Ethanol Production (November 9, 2016)
- Non-bruising GE Potato Cleared for Sale by USDA (November 3, 2016)
- TALENs-mediated Targeted DNA Insertion Approach for Potato (October 12, 2016)
- How Can TALENs Help Feed the World by 2050? (December 14, 2022)
- What You Need to Know About TALENs (March 24, 2021)
- First Commercialized Gene-edited Plant Developed Using TALENs (January 13, 2021)
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