Scientists Use CRISPR to Grow Human Pancreas in PigsJune 15, 2016
Researchers from the University of California, Davis, are using CRISPR gene editing and induced pluripotent stem (IPS) cells to create a hybrid pig-human embryo to grow human organs.
The hybrid embryo is known as a chimera, and would act and look like a normal pig, but will have a pancreas made of human cells. One day the process could grow life-saving organs for humans. Scientists did it by deleting parts of the fertilized pig DNA using CRISPR, and then filling this hole by injecting human iPS cells so that a human pancreas can grow.
There has been concern that animal viruses could be transferred to humans through transplantation. However, Harvard Medical School scientists showed it was possible to inactivate more than 60 retrovirus genes in pigs using gene-editing technology.
One possibility is if a patient's IPS cells were donated and combined with the pig embryo, creating a copy of the person's own organ that would lead to a more successful transplant.
For more on this topic, read the article on Bioscience Technology.
The Crop Biotech Update is a weekly newsletter of ISAAA, a not-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- Final Analysis Shows 100% Compliance of Parties to Kyoto Protocol
- G20 Ministers: Innovation in Agriculture the Key to Ending Extreme Hunger
- IWGSC Releases Wheat Sequence Repository for Wheat Researchers
- Study Reveals Experts' Attitudes towards Governance of Gene Editing
- ICRA: Pricing Controls and Compulsory Licensing of Bt Cotton Cloud the Long-term Growth of GM Seeds Industry
- Research Findings Bring Promise of Tailored Products for the Industry
- New Plant Engineering Method to Help Mass Production of Malaria Drug
- MfPIP2-7 Gene from Falcate Confers Cold Tolerance in Transgenic Tobacco
- Overexpression of Wheat Gene Improves Abiotic Stress Tolerance in Stiff Brome
Beyond Crop Biotech
- Plant-based Vaccine a Front Runner for New Polio Jab
- Scientists Use CRISPR to Grow Human Pancreas in Pigs
From the BICs
- ISAAA Report Launched in Kenya
- Postgraduate Course in Biosafety in Plant Biotechnology
- What are CRISPR/Cas9 and other New Breeding Technologies (NBTs)?
- The Necessary "GMO" Denialism and Scientific Consensus
Read the latest:
- Crop Biotech Update (September 21, 2022)
- Genome Editing Supplement (September 21, 2022)
- Gene Drive Supplement (August 31, 2022)
Subscribe to CBU: