Plant-based Vaccine a Front Runner for New Polio JabJune 15, 2016
Professor George Lomonossoff of The John Innes Centre, is part of a research project led by the University of Leeds that aims to develop safer polio vaccines without using the live virus and exploring different methods for their production.
Professor David Rowlands, of the University of Leeds' Faculty of Biological Sciences, who leads the project together with Professor Nicola Stonehouse, said that their approaches create stable vaccines effective against the virus in the lab, but they need to be manufactured in a cost effective manner. "The fundamental challenge is to build protein shells that are the same as the virus' but that do not have any of the genetic material of the virus," they added. The problem with this approach is that, the empty virus-like particles (VLPs), they have developed have been less stable than the complete virus, and are not suitable for making vaccines.
Professor Lomonossoff said that growing large quantities of VLPs in plants is surprisingly easy and incredibly efficient. "You simply introduce bacteria containing the genes for the VLP into the plant, which results in the plant's cells making many copies of the VLP. The process, from introduction of the bacteria to harvesting the VLPs from the crushed leaves can take just a matter of weeks." He added that this technique has a lower risk of contamination with other human viruses.
For more details, read the news release at The John Innes website.
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- Final Analysis Shows 100% Compliance of Parties to Kyoto Protocol
- G20 Ministers: Innovation in Agriculture the Key to Ending Extreme Hunger
- IWGSC Releases Wheat Sequence Repository for Wheat Researchers
- Study Reveals Experts' Attitudes towards Governance of Gene Editing
- ICRA: Pricing Controls and Compulsory Licensing of Bt Cotton Cloud the Long-term Growth of GM Seeds Industry
- Research Findings Bring Promise of Tailored Products for the Industry
- New Plant Engineering Method to Help Mass Production of Malaria Drug
- MfPIP2-7 Gene from Falcate Confers Cold Tolerance in Transgenic Tobacco
- Overexpression of Wheat Gene Improves Abiotic Stress Tolerance in Stiff Brome
Beyond Crop Biotech
- Plant-based Vaccine a Front Runner for New Polio Jab
- Scientists Use CRISPR to Grow Human Pancreas in Pigs
From the BICs
- ISAAA Report Launched in Kenya
- Postgraduate Course in Biosafety in Plant Biotechnology
- What are CRISPR/Cas9 and other New Breeding Technologies (NBTs)?
- The Necessary "GMO" Denialism and Scientific Consensus
Read the latest:
- Biotech Updates (May 24, 2023)
- Gene Editing Supplement (May 24, 2023)
- Gene Drive Supplement (February 22, 2023)
Subscribe to BU: