Scientists Use Metabolic Engineering to Modify Omega-3 Fatty Acids in MicroalgaeJanuary 15, 2014
Scientists from Rothamsted Research have used metabolic and genetic engineering to demonstrate for the first time that it is possible to achieve an eight-fold increase in DHA content in Phaeodactylum tricornutum. The diatom P. tricornutum naturally accumulates high levels of EPA and is considered a good source for industrial production. The study is published in the journal Metabolic Engineering.
Marine microalgae and diatoms are the primary producers of eicosapentaenoic acid (EPA) and docosahexanoic acid (DHA) long chain polyunsaturated fatty acids (LC-PUFAs) in the aquatic food web. Marine microalgae cultivation is one of the sources of these oils. Currently, no single algal strain accumulates high concentration of EPA and DHA.
The researchers used two genes from the picoalga Ostreococcus tauri in the diatom P. triconutum and successfully altered the Omega-3 content in the latter. They developod a strain of the diatom that can now accumulate both EPA and DHA. Naturally, the diatom produces ~35% EPA and only traces of its total oil content. The newly developed transgenic diatom strain can convert a substantial portion of the EPA that they make to DHA. Therefore, scientists have successfully generated the first transgenic diatom that can synthesize both of these high value omega-3 LC-PUFAs.
See Rothamsted Research's news release at http://www.rothamsted.ac.uk/news/single-diatom-accumulates-epa-and-dha-high-value-omega-3.
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- Major Economic Models Point Direction on World's Agriculture, Climate Change
- Biotic Stress: From Gene to Field
- Adesina Calls on Speeding Up Biosafety Bill Approval
- TWAS-ARO Organize S&T Education for Sustainable Development in Arab Region Conference
- US Consumers' Perception of Biotech Crops
- General Mills' Cheerios Reinforce Safety of Biotech Crops
- Fraley: Biotech Wheat Moves Closer to Market
- Researchers Discover Another Pathway for Amino Acid Production in Plants
- Indian National Science Academy Fellowship Conferred on ICRISAT Scientist
- Scientists Discover Plant Mechanism to Stimulate their Growth Even Under Stress
- EFSA: GM Soybean 305423 is as Safe as its Conventional Counterpart
- Wheat Genome Dataset to Help Researchers Improve the Grain
- Overexpression of Glucanase in Maize for Direct Use in Animal Feed
- Gene from Arabidopsis Improves Drought Tolerance of Indica Rice
- Effect of Biotech Maize 5307 on Non-target Organisms
Beyond Crop Biotech
- Coppicing Response Gene in Biomass Willow Identified
- Scientists Use Metabolic Engineering to Modify Omega-3 Fatty Acids in Microalgae
- 2nd Plant Genomics Congress
- 5th World Congress on Biotechnology
Read the latest:
- Biotech Updates (February 1, 2023)
- Genome Editing Supplement (January 18, 2023)
- Gene Drive Supplement (January 25, 2023)
Subscribe to BU: