Crop Biotech Update

Scientists Successfully Edit Dengue Fever Mosquito Genes

September 9, 2015

Researchers at the University of Missouri (MU) have found an effective way to edit the genes of dengue virus transmitting Aedes aegytpi mosquitoes. The researchers used the CRISPR/Cas9 gene editing system to disrupt the blue fluorescent eye color gene in a previously generated genetically modified mosquito line, which originally expressed both fluorescent blue and red color genes in their eyes. Future generations of these mosquitoes no longer showed the blue color, but still exhibit the red color expression in their eyes.

Alexander Franz, assistant professor of veterinary pathobiology at MU and senior author of the study, said that future research using this technique could search for ways to genetically edit mosquitoes so they cannot harbor diseases like dengue.

For more details about this study, read the news release at the University of Missouri website.