Preventing Post-injury Arthritis Using Stem Cells
August 29, 2012| |
Injuring a joint greatly raises the odds of getting a form of osteoarthritis called post-traumatic arthritis, or PTA. There are no therapies yet that modify or slow the progression of arthritis after injury. Dr. Farshid Gilak director of orthopedic research department at Duke University and several of his colleagues found a very promising therapeutic approach to PTA which was published in Cell Transplantation. Their method involves using a type of stem cell, called mesenchymal stem cells (MSCs) which they tested in mice with fractures that typically would lead to them developing arthritis.
The scientists thought the stem cells would work to prevent PTA by altering the balance of inflammation and regeneration in knee joints, because these stem cells have beneficial properties in other regions of the affected part of the body. Their findings could lead to a therapy that would be used after joint injury and before signs of significant osteoarthritis.
See the news in Farsi at http://isna.ir/fa/news/91052414841/. The English translation was provided by Nagmeh Abiri of Iran BIC at nmabiri@gmail.com.
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