Cas-CLOVER, an Alternative to CRISPR-Cas9
April 15, 2020| |
CRISPR-Cas9 has been the most used gene editing system used for genetic improvement of plants, animals, and other organisms. A new gene editing technology called Cas-CLOVER was presented in a webinar held by Genetic Engineering and Biotechnology News (GEN) on April 14, 2020.
Cas-CLOVER, developed by Hera BioLabs, is functionally similar to CRISPR-Cas9 but uses a different nuclease protein called Clo51. Thus, Cas-CLOVER is a fusion protein that comprises a nuclease-inactivated Cas9 protein fused to the Clo51 endonuclease. Compared to CRISPR-Cas9, it demonstrates higher fidelity with no detectable off-targets while maintaining robust editing efficiency.
Read more about Cas-CLOVER from Hera BioLabs and GEN.
| |
You might also like:
- Plant Breeding Innovation: CRISPR-Cas9
- Another CRISPR Tool Shows Great Potential to Advance Science
- Scientists Report Functionally Diverse Type V CRISPR-Cas Systems
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
-
See more articles:
-
News from Around the World
- International Research Team Discovers Gene to Develop Fusarium Head Blight Resistant Wheat
- Five Countries Produce More than 90% of Biotech Crops Worldwide
- FSANZ Says New GM Soybeans Safe, Invites Public for Comments
- Rothamsted Research Makes Breakthrough in Fight Against Weeds
- Plant-based Tuna Rolls Out for Sushi Lovers
-
Research Highlights
- New Source of Powdery Mildew Resistance Found in Wild Wheat
- Vitamin E-enriched Sweet Corn Developed
-
Plant
- Gene Editing Could Yield Herbicide Tolerant, Non-GM Soybeans
- Cas-CLOVER, an Alternative to CRISPR-Cas9
-
Health
- Researchers in Spain Use Biotech to Produce SARS-CoV-2 Vaccine in Plants
-
Read the latest: - Biotech Updates (June 11, 2025)
- Gene Editing Supplement (May 28, 2025)
- Gene Drive Supplement (February 22, 2023)
-
Subscribe to BU: - Share
- Tweet