Identification of Candidate Genes for Calanolide Synthesis in Santa Maria TreeAugust 24, 2016
Santa Maria (Calophyllum brasiliense) is an important source of calanolides, which inhibit the reverse transcriptase of human immunodeficiency virus type 1. Despite its great medicinal importance, enzymes involved in calanolide as well as its biosynthetic pathway are still unknown.
Hilda-Beatriz Gómez-Robledo from Universidad Anáhuac in Mexico and colleagues analyzed the transcriptome of C. brasiliense leaves, stem, and roots. Using the transcriptome dataset as well as the structures of the calanolides, the team proposed several biosynthetic pathways to study. Finally, candidate genes in the dataset potentially involved in the calanolide biosynthetic pathway were recorded.
The data generated in this study could serve as an important basis for further molecular studies of C. brasiliense, especially for functional analysis of candidate genes involved in biosynthetic pathway of calanolides.
For more information on this study, read the full article in BMC Plant Biology.
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- Africa's Biosafety Agencies Seek to Harmonize Approaches to Regulatory Systems
- African Countries Strive to Meet Int'l Biosafety Obligations
- Photosynthesis Discovery in Wheat to Yield Faster Growing Crops
- Australia's OGTR Receives Application for Field Trials of Biotech Cotton
- Murdoch University Researchers Increase Wheat Protein to More than 14%
- European Seed Association Asks EU to Recognize Role of Plant Breeding in Addressing Societal Challenges
- EFSA Publishes Public Opinion for Market Release of Pioneer GM Soybean
- CIP Develops Marker-free PLRV Resistant Potato
- Researchers Map QTL for Dwarf Architecture in Oilseed Rape
Beyond Crop Biotech
- Identification of Candidate Genes for Calanolide Synthesis in Santa Maria Tree
- MOOC: Science and Politics of the GMO
- IUMS Congresses 2017
- Biotech Country Facts and Trends
- Swiss Academies: Strict Regulations Not Necessary for NBTs
- Broad Virus Resistance in Cucumber Developed using CRISPR
Read the latest:
- Biotech Updates (September 20, 2023)
- Gene Editing Supplement (September 13, 2023)
- Gene Drive Supplement (February 22, 2023)
Subscribe to BU: