Biotech Updates

Genome-Wide Analysis of the Cassava Transcriptome

October 31, 2008

Cassava (Manihot esculenta Crantz) is a tropical crop plant widely cultivated for its thick starchy roots. In Thailand, cassava ranks as one of the most important economic crops along with rice, rubber tree and sugar cane. The inadequate knowledge of the genetic regulatory networks governing the biosynthesis of starch is a major obstacle in post-harvest modification of cassava starch.

A collaborative research effort between Thailand’s BIOTEC and Japan’s Nara Institute of Science and Technology is to establish a large cassava EST collection. The information garnered from the EST repertoire would help gain preliminary insights into the state and flux of the cassava transcriptome under various circumstances known to influence the starch metabolism in plants. After thorough analysis of the database, non-redundant EST sequences would be selected and used in the fabrication of cassava microarray chips for global analysis of the cassava transcriptome. It is expected that many novel and important genes involved in several vital traits, e.g. the starch quality and quantity, could be identified from this research effort.

The complete article is available at http://www.safetybio.agri.kps.ku.ac.th/index.php?option=com_content&task=view&id=3851&Itemid=47