Scientists Report Functionally Diverse Type V CRISPR-Cas Systems
January 16, 2019| |
CRISPR-Cas9 systems have been the "talk of the town" in various fields involving gene editing. Researchers from Arbor Biotechnologies and National Institutes of Health in the USA searched the metagenomic database and systematically found two more subtypes of type V CRISPR-Cas systems. The results are published in Science.
According to the report, the additional Cas12 effectors exhibit a range of activities, including target and collateral cleavage of single-stranded RNA and DNA, as well as double-stranded DNA nicking and cleavage. Such diversity of nuclease activities may imply how an ancient transposase may have evolved into various type V effectors and broaden the nucleic acid detection and CRISPR toolbox.
Read more information from Science.
| |
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
-
See more articles:
-
News from Around the World
- Blueprint for Plant's Immune Response has been Found
- Scientists Identify How Plants Sense Temperature
- Research Finds Extreme Opponents of GM Foods Know the Least but Think They Know the Most
- NRGene and Toyota Decode Strawberry Genome to Develop Better Varieties
- Approval of Monsanto's GM Cotton Seed Patent to Boost India's Biotech Industry
- Mechanism Behind Plant Memory has been Unraveled
- Improved Crops Can Double Agricultural Production in Europe
- EFSA: GM Maize (MON 89034x1507xMON 88017x59122xDAS-40278-9) and Soybean (A2704-12) are Safe for Release
-
Research Highlights
- Rice Plants Engineered for Better Photosynthesis Make More Rice
- Meta-analysis of Soil Enzymatic Responses to Bt Crops
-
Beyond Crop Biotech
- Gene-edited Tilapia Not Classified as GMO in Argentina
- Biotechnology to Possibly Address Forest Health Problems
-
Resources
- Bt Brinjal: The Bangladesh Experience
-
Plant
- Scientists Report Functionally Diverse Type V CRISPR-Cas Systems
- Gene Editing for Developing GM Spicy Tomatoes
-
Read the latest: - Biotech Updates (October 2, 2024)
- Gene Editing Supplement (September 26, 2024)
- Gene Drive Supplement (February 22, 2023)
-
Subscribe to BU: - Share
- Tweet