Study Finds Plants Reprogram Their Genetic Material to Fight PathogensJuly 26, 2017
An international research team led by Heribert Hirt from King Abdullah University of Science and Technology (KAUST) has found the missing link in the complex molecular pathway by which plants resist pathogens.
Using Arabidopsis, the team activated mitogen-activated protein kinases (MAPKs) using a bacterial microbial-associated molecular patterns (MAMPs). In a series of experiments, they searched for phophorylation events and found that the final MAPK-MAPK in the chain which is MPK3, phosphorylates the enzyme histone deacetylase (HD2B), which regulates DNA compaction into chromatin.
The team showed that in Arabidopsis plants that lack MPK3 or HD2B, many defense genes increased in activity, suggesting that HD2B represses gene activity. When pathogens attack, MPK3's action on HD2B reverses this repression.
Hirt said that kinase-triggered chromatin reprogramming is a widespread mechanism, and considers possibilities for artificially stimulating this process. "Once we better understand the mechanism of inducing pathogen memory, we might be able to induce long-term resistance, similar to human vaccination," he added.
For more details, read the KAUST Discovery.
The Crop Biotech Update is a weekly newsletter of ISAAA, a not-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- Web Portal Established to Speed up Genetic Research in Plants
- India's B.R. Barwale Passes Away
- African Biosafety Regulators Embrace Biosafety Communication at ABBC 2017
- Biotechnology Praised at the Biggest Agri Expo in Uganda
- Adoption of GE Crops in the US
- New Gene in Corn Confers Resistance to Multiple Diseases
- Study Finds Plants Reprogram Their Genetic Material to Fight Pathogens
- China Gives Import Approval for Corn Rootworm Resistant Trait
- Russia Drafts Regulations for GE Feed
- Overexpression of BoC3H Gene Enhances Salt Stress Tolerance in Broccoli
- Study on the Effect of Light and Temperature on CBF14 Expression in Wheat and Barley
Plant Breeding Innovations
- CRISPR-Cas9 and CRISPR-Cpf1 Mediated Genome Editing of EPFL9 Gene in Rice
- Discovery on How CRISPR Proteins Identify Targets
Beyond Crop Biotech
- NAS Announces Awards for Science Communication
- Researchers Develop Plant-produced Vaccine Candidates Against Bluetongue Virus
Read the latest:
- Crop Biotech Update (August 10, 2022)
- Genome Editing Supplement (August 10, 2022)
- Gene Drive Supplement (July 27, 2022)
Subscribe to CBU: