Transgenic Expression and Recovery of Biologically Active Recombinant Human Insulin from Thale Cress Seeds
November 5, 2010| |
With the increased incidence of diabetes comes the increased demand for affordable insulin in the future. However, limitations in the capacity and economics of production will make it difficult for the existing manufacturing techniques to reach the demand for insulin. Thus, scientists are finding novel ways to produce insulin to meet the future demand. SemBioSys Genetics, Inc. scientist Cory Nykiforuk and colleagues developed a new expression and recovery technique for the economical production of biopharmaceuticals from oilseeds. Through this technology, recombinant human precursor insulin is expressed in genetically-engineered plants. Plant-produced insulin accumulates to significant levels in GE thale cress seed (0.13 percent total seed protein) and can be treated in a controlled environment to form a product which is equally effective as DesB30-insulin, a recombinant human insulin protein product.
Read the research article published by the Plant Biotechnology Journal at http://onlinelibrary.wiley.com/doi/10.1111/j.1467-7652.2005.00159.x/full.
| |
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
-
See more articles:
-
News from Around the World
- FAO Cites Use of 'Climate Smart' Agriculture
- More CBU Subscribers Receive Replica of Norman Borlaug Congressional Medal
- Floods Cause Food Crisis in Sokoto, Jigawa, Kebbi
- UN Report Says Africa Making Gains in Human Development Index
- Chromosome Imbalances Cause Predictable Plant Defects
- USDA Prepares Draft EA on Regulatory Options for RR Sugar Beets
- U of I Scientists Discover Potential New Virus in Switchgrass
- Biotechnology in Fruits and Vegetables: A Lot of Research, Few Approvals
- Developmental Tool for Algae-based Biofuels
- Pioneer Introduces 29 New Soybean Varieties for 2011
- Pioneer and Int'l Federation of Agri Journalists Announce Global Journalism Project
- Cellectis Plant Sciences Plant Transformation Technology for Corn and Rice
- India's National Bureau of Plant Genetic Resources Appoints New Director
- India to Accelerate Adoption of Stress-tolerant Rice Varieties
- Korea Approves New Biotech Crops
- Learning from Brazil's Agricultural Success
- IPR and Private Investment in India
- Biotechnology: EU Commission for 0.1 Percent Tolerance in Feed Imports
- Organic Vegetables Don't Have Higher Levels of Healthful Antioxidants
- UK Farm Emission Research to Reduce Impact of Climate Change
-
Research Highlights
- Bt Rice Lines Exhibit High Yield Amidst Insect Pressure
- Expression of Biotin-binding Proteins in GM Tobacco confers Resistance to Potato Tuber Moth
- Transgenic Expression and Recovery of Biologically Active Recombinant Human Insulin from Thale Cress Seeds
-
Resources
- Workshop Presentations on Monitoring Cultivation of GM Crops
-
Read the latest: - Biotech Updates (April 30, 2025)
- Gene Editing Supplement (April 30, 2025)
- Gene Drive Supplement (February 22, 2023)
-
Subscribe to BU: - Share
- Tweet