Researchers Invent New Gene Editing ToolMarch 3, 2021
Researchers from the University of Illinois Chicago (UIC) have discovered a new gene editing technique that allows for the programming of sequential cuts — or edits — over time.
The new process developed by UIC's Bradley Merrill, lead author of the paper published in Molecular Cell, involves using special molecules called guide RNA that ferry the Cas9 enzyme within the cell and determine the precise DNA sequence at which Cas9 will cut. They call their specially engineered guide RNA molecules "proGuides," and the molecules allow for the programmed sequential editing of DNA using Cas9.
Merrill said that a drawback of currently available CRISPR-based editing systems is that all the edits or cuts are made all at once and there is no way to guide them so that they take place in a sequential fashion, which proGuides allows. While proGuide is still in the prototype phase, Merrill's team plans to further develop their concept and hopes that researchers will be able to use the technique soon.
For more details, read the article in UIC Today.
You might also like:
- New Genome Editing Tool Designed to Make Big DNA Edits
- Harvard, MIT Experts Develop New Gene Editing Technology
- New CRISPR System Enables Temporary Gene Editing
The Crop Biotech Update is a weekly newsletter of ISAAA, a not-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
- Survey Shows People with Low Scientific Reasoning Tend to Believe Conspiracy Theories on COVID-19
News from Around the World
- FAO DG Outlines "Four Betters" as Strategy to Transform Agri-food Systems
- ISAAA Report Summary Now Available in Indonesian, Chinese, Thai, and Vietnamese
- Science-based Ag-biotech Curriculum Developed for Middle, High School Students in the US
- Wheat's 'Second Genome' Could Help in the Plant's Survival against Environmental Stress
- Study Reveals Plant Clock Key to Producing More Food for the World
- Asian Biotechnology Information Centers Pledge to Advance Biosciences
- Researchers Identify Mechanism that Protects Plant Fertility from Stress
- NtCIPK11 Confers Salt and Drought Tolerance in Arabidopsis
Plant Breeding Innovations
- CRISPR-Cas9 Could Provide the Much-needed Help on Food Security against Climate Change
- UK Scientists Develop Genome-edited Wheat to Reduce Cancer Risk from Bread
- Researchers Invent New Gene Editing Tool
Read the latest:
- Crop Biotech Update (May 25, 2022)
- Genome Editing Supplement (May 18, 2022)
- Gene Drive Supplement (May 25, 2022)
Subscribe to CBU: