Scientists Reveal a Gene Related to Alzheimer's Disease Using CRISPR
November 7, 2018| |
Cases of Alzheimer's disease (AD), the most common form of dementia, is mostly sporadic, making it difficult for scientists to determine how the disease starts and develops. Notably, researcher Carlos Pascual-Caro from University of Extremadura in Spain and colleagues pave a step forward into finding a cure for the disease by discovering a gene linked to Alzheimer's.
In their article published in Journal of Molecular Medicine, they described the discovery of the STIM1 gene and how CRISPR helped in verifying its function and mechanism. By analyzing brain tissues from deceased AD patients and normal patients, researchers found deficiency in STIM1 in AD patients. Through CRISPR, the researchers discovered that deletion of the gene results to reduced transport of calcium ions through the plasma membrane, which causes the cell to die.
For more information, read the articles in Synthego and Journal of Molecular Medicine.
| |
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
-
See more articles:
-
News from Around the World
- 13 WTO Members Support Policy Approaches to Enable Innovation in Agriculture
- Farmers and University Students Call for Urgent Action on Biotech Legislation in Uganda
- US Patent Awarded to DNA-Targeting Complex
- High Temperatures Can Trigger a Reaction in a Plant's RNA
- ASTA Lauds International Statement Supporting of Plant Breeding Innovation
- Scientists Discover Gene Regulator that Allows Plant to Rehydrate After Drought
- FAS Jakarta Launches "Biotech Ambassadors" Outreach
- USDA: The Philippines Remains as Asia's Leader in Biotech
- Gene Discovery Could Pave Way for Disease Resistant Crops
- Small Genetic Differences Make Plants into Better Teams
- Agriculture Minister of The Netherlands Opens Door to Genetic Modification
-
Research Highlights
- Protoplast Isolation Method for Genetic Improvement of Pineapple
- Gene from Castor Bean Increases Unusual Oil in Camelina
-
Beyond Crop Biotech
- Scientists Reveal a Gene Related to Alzheimer's Disease Using CRISPR
-
Resources
- Pocket K: Contributions of Agri-biotech in Alleviation of Poverty and Hunger (Updated)
-
Plant
- Researchers Use CRISPR for Apple and Grapevine Improvement
- Plasmid-Free Genome Editing of Cabbage and Chinese Cabbage
- Plant Genome Editing Database (PGED) Goes Live
-
Read the latest: - Biotech Updates (April 24, 2024)
- Gene Editing Supplement (April 24, 2024)
- Gene Drive Supplement (February 22, 2023)
-
Subscribe to BU: - Share
- Tweet