Mosquitoes that Self DestructNovember 22, 2017
University of California, Riverside (UCR) researchers have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. Cas9 enables the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA.
The researchers used CRISPR to disrupt cuticle, wing, and eye development, producing completely yellow, three-eyed and wingless mosquitoes. Their long-term goal is to use Cas9-expressing mosquitoes together with gene drives to insert and spread genes that suppress the insects while avoiding the resistance that evolution would typically favor. Aedes aegypti are major carriers of dengue, chikungunya, yellow fever, and zika viruses, and are rapidly becoming resistant to commonly used pesticides.
The study was led by Omar Akbari, assistant professor of entomology in UCR's College of Natural and Agricultural Sciences. He said these strains represent the first step towards using gene drive systems to control mosquito populations and reduce the diseases they spread.
For more details, read UCR Today.
The Crop Biotech Update is a weekly newsletter of ISAAA, a non-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- International Food Biotechnology and Biosafety Workshop Releases Final Declaration
- Nigeria Stakeholders Embrace Bt Cotton as a Solution for Revamping the Textile Industry
- Researchers Identify Gene that Enables Wheat Resistance to Stem Rust
- Australian OGTR Releases Report on 2017 Study of Public Attitudes about GMOs, Gene Technology and its Regulation
- Senior High School Students and Teachers Take Part in Agri-biotech Boot Camp
- The Biotechnology and Bioeconomy Landscape in Malaysia
- QUT Grows World's First Panama Disease-Resistant Bananas
- Food Evolution Enlightens Filipino Students and Stakeholders on Global GMO Discussion
- EFSA Says Yes to Reauthorization for GM Sugar Beet in the EU
- microRNA159 Impacts Multiple Agronomic Traits in Rice
- Tomato Immune Receptor Ve1 Confers Ave1-dependent Verticillium Resistance in Tobacco and Cotton
Plant Breeding Innovations
- Scientists Evaluate the Use of CRISPR-Cas9 on Date Palm
Beyond Crop Biotech
- Mosquitoes that Self Destruct
- Burkinabe GM Mosquito Malaria Eradication Project Gets off to a Good Start
- 2017 Conservation Tillage Conference
Subscribe to CBU: