Genome Reprogramming for Synthetic BiologyMarch 22, 2017
The ability to go from a digitized DNA sequence to a predictable biological function is the main principle in synthetic biology. Genome engineering tools enable rewriting and implementation of engineered DNA sequences. The recent developments of new programmable tools to engineer genomes have also sparked a multitude of advances in synthetic biology.
These tools, such as the CRISPR-Cas9 system, enable RNA-guided redesign of organisms and the execution of synthetic gene systems. These new directed evolution methods generate organisms with radically restructured genomes, including restructured organisms with useful new phenotypes for biotechnology, such as bacteriophage resistance and increased genetic stability. Advanced DNA synthesis and assembly methods have also made possible the construction of fully synthetic organisms.
Arizona State University's Kylie Standage-Beier recently summarized these recent advances in programmable genome engineering tools as well as their impact on synthetic biology.
For more on this paper, read the article in Frontiers of Chemical Science and Engineering.
The Crop Biotech Update is a weekly newsletter of ISAAA, a not-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- NAS Releases Report on Preparing for Future Biotech Products
- East Africa Gears for Synthetic Biology
- Egypt Hosts the International Conference on Biotechnology and Environmental Safety
- Discovery by Researchers Could Help Increase Plant Yield Caused by Looming Phosphate Shortage
- International Research Team Discovers Gene that Resists Virus Causing Maize Lethal Necrosis Disease
- VIB-UGent Researchers Discover Gene that Increases Seed Yield in Maize
- European Chemicals Agency Says Glyphosate Not Carcinogenic
- Production of Antibacterial BP178 Peptide in Rice Seed Endosperm
- MADS-box Gene SlMBP11 Regulates Plant Architecture and Reproductive Development in Tomato
Plant Breeding Innovations
- Genome Reprogramming for Synthetic Biology
- Researchers Generate Nulliplex Polyploid Arabidopsis using CRISPR-Cas9
Beyond Crop Biotech
- Cell-Penetrating Peptide-Mediated Delivery of CRISPR-Cas9
- Being Human 2.0: SynBio LIVE
- The Story Behind the Approval of the First Bt Maize Product
- Synthetic Biology MOOC Teaches How to Make DIY DNA
Read the latest:
- Crop Biotech Update (May 25, 2022)
- Genome Editing Supplement (May 18, 2022)
- Gene Drive Supplement (May 25, 2022)
Subscribe to CBU: