OSU Scientists Discover Protein Linked to Spread of Breast Cancer CellsApril 2, 2014
Researchers at the Ohio State University (OSU) discovered a protein that was not previously linked to cancer has an important role in reducing the chances for the disease to extend beyond the initial tumor.
The study published in PLOS ONE showed that mice implanted with breast cancer cells lacking the protein myoferlin produced small, self-contained tumors of cells that didn't leave the tumor. On the other hand, mice implanted with cancer cells with myoferlin developed larger, irregular masses and manifested that cancer cells had invaded the nearby tissues. Based on the observations, myoferlin affects cancer cells in two ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells so they are more likely to remain nested together rather than breaking away to travel to other tissues.
Scientists could use the findings in developing diagnostic methods and treatments tailored to patients based on protein levels and mechanical properties in cells detected in tumors.
Read the original article at http://researchnews.osu.edu/archive/myoferlin.htm
The Crop Biotech Update is a weekly newsletter of ISAAA, a non-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- New International Partnership Aims to Increase Wheat Yields
- ISAAA Report on GM Crops Launched in Burkina Faso, South Africa, and Kenya
- Uganda Launches 2013 Global Status Report
- UN Announces First Countries Set to Benefit from African-Led Food Security Fund
- FAO DG: Africa's Youth Key to Strengthening Agricultural Economy
- ACSH Releases New Publication on GM Food
- Engineered Bacteria Produce Biofuel Alternative for Rocket Fuel
- Philippine DA Regulators and Crop Researchers Train on Biotech Communication
- Vietnam's Regulatory Circular to Take Effect
- GEAC Allows Field Trials of 11 New Varieties of Biotech Crops in India
- BARI DG Faced the Media on Bt Brinjal Commercialization
- ISAAA Produces Infographic on "7 Wonders of Bt Cotton"
- Scientists Identify Sugar Transporter for Nectar Production
- GOLDEN2-LIKE Transcription factors: Keys to Tomato Development
- Genetic Analysis of Verticillium Wilt Resistance in Biotech Cotton
Beyond Crop Biotech
- Study Finds Math Anxiety Can be Due to Genetic Factors
- OSU Scientists Discover Protein Linked to Spread of Breast Cancer Cells
- Synthetic Biology Congress
- World Congress on Industrial Biotechnology
Top Ten Facts on Global Biotech/GM Crops 2013 in 52 Languages
Subscribe to CBU: