Biotech Updates

Protein Structures Give Disease Clues

February 10, 2012

Researchers at UC Davis recently found evidence that the systems operating similar to lock and key in proteins, could give insights on how diseases are developed and could lead to ways for treating and preventing cancers and Alzheimer's disease.

A series of research findings published last month and the results of new studies published in Nature and Journal of Biological Chemistry reveal that two protein channels inositol triphosphate receptor and the ryanodine receptor are similar in structure and binds to the stimuli molecule to release calcium inside the cell. There are evidences to show that calcium concentrations in cells are associated with the occurrence of breast cancer, Parkinsons and Alzheimer's diseases among others.

Researchers hope that understanding how inositol triphosphate triggers calcium flows, and how that process might be boosted or blocked, will lead to new ways to treat neurodegenerative diseases.

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