Crop Biotech Update

Degradation of Cry1Ab Protein from GM Maize in the Digesta of Dairy Cows

September 3, 2010

Technische Universitaet Muenchen scientist Heinrich H. D. Meyer and colleagues investigated the relative degradation and fragmentation pattern of the recombinant Cry1Ab protein from genetically modified maize MON810 in the gastrointestinal tract of dairy cows. Two groups of lactating Bavarian Fleck cows went through a feeding study, wherein one group was fed with GM maize, while the other group was fed with non-GM maize. During the trial, feed and feces samples were collected from representatives of each group. After the trial, the cows were slaughtered and then the food from the different parts of the cows' gastrointestinal tract were collected. The researchers analyzed the total protein and Cry1Ab protein from the samples. Results showed that Cry1Ab is increasingly degraded during the dairy cow digestion. Compared with the total protein in feed, the relative amount of Cry1Ab protein in feces is significantly decreased, which implies that Cry1Ab is less stable than the other proteins in the feed of dairy cows.

Read more about this study in the current issue of Transgenic Research Journal available at