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UQ Researchers Reveal RNA-Based Biopesticides Can Travel from Leaves to Roots

February 18, 2026

Dr. Chris Brosnan (left) and Dr. Donald Gardinar in the QAAFI laboratory. The researchers have discovered that double-stranded RNA-based biopesticides (dsRNA) sprayed on plant leaves can travel into the root system. Photo Source: Megan Pope

Researchers at the University of Queensland have made a breakthrough discovery revealing that RNA-based biopesticides sprayed on leaves can travel systemically through a plant to its roots. This finding challenges long-held scientific assumptions and opens the door to protecting crops from underground threats such as nematodes and fungi with sustainable, chemical-free sprays.

The study, led by Dr. Chris Brosnan at the Queensland Alliance for Agriculture and Food Innovation (QAAFI), found that double-stranded RNA (dsRNA) does not simply enter individual cells where it is applied. Instead, it moves between cells and throughout the plant's vascular system as an intact molecule. This systemic mobility is a game-changer for agricultural technology, as it provides a potential delivery mechanism for biopesticides to reach deep into root systems, an area that has historically been incredibly difficult to treat with traditional sprays.

By using RNA interference (RNAi) to shut down essential genes in specific pests without harming the plant or beneficial insects, this technology offers a targeted alternative to synthetic chemicals. QAAFI's Dr. Donald Gardiner noted that the research challenges the dogma that RNA is unstable and difficult to take up in soil, where it is often fragile and easily degraded. By moving through the plant's own tissues rather than the surrounding environment, the RNA-based treatment could soon provide a powerful new tool to safeguard global food security against previously out-of-reach pathogens.

For more details, read the article on The University of Queensland News.


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