Biotech Updates

Study Shows Information Beyond Genetic Code is Stored in Plant Sperm

July 7, 2021

Photo Source: John Innes Centre

Researchers from John Innes Centre identified a mechanism which adjusts modifications in the DNA to alter the way information beyond the genetic sequence is passed down onto next generations.

The researchers have discovered the mechanism of DNA methylation in reprogramming the male germ line of Arabidopsis plants. DNA methylation is an example of epigenetic modification. It happens when a methyl group is added to the DNA to switch a gene on or off. As the germ line cells develop, some of the methyl markers are reset which affects the information passed on to its offspring. The researchers also found the protein, CLSY3, in the tapetal cells in the anther that causes the production of large amounts of small RNA molecules to nourish the cells which divide to form the sperm in the anthers.

The small RNA molecules were shown to move from tapetal cells into the sperm. The researchers then added new methyl marks to unstable genetic elements with the same DNA code to prevent the unstable genes from jumping around the germ cells and protecting the integrity of the genome between generations.

The results of the study could help develop new biotechnology approaches in seed formation and breeding in commercial crops such as maize and rice because these crops were shown to have similar tapetal cells with Arabidopsis.

For more details, read the press release of the John Innes Center and the journal article in Science.

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