UConn Researcher Develops Simple, Low-Cost CRISPR-based Diagnostic Test for COVID-19 |
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Researchers at the University of Connecticut's Department of Biomedical Engineering are working to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including the novel coronavirus (SARS-CoV-2). Associate Professor Changchun Liu developed the "All-In-One-Dual CRISPR-Cas12a" (AIOD-CRISPR) method to enable simple, rapid, ultrasensitive, visual detection of SARS-CoV-2 and HIV viruses, intended for use at home or in small clinics.
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Scientists Optimize Prime Editing for Rice and Wheat |
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David R. Liu and his colleagues at Harvard University have developed prime editing, a new genome editing approach, which uses engineered Cas9 nickase (H840A)-reverse transcriptase (RT) fusion proteins paired with a prime editing guide RNA (pegRNA). Prof. Gao Caixia and his team at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences reported the optimization of a prime editing system (PPE system) for creating desired point mutations, insertions, and deletions in two major cereal crops, rice, and wheat. The main components of a PPE system are a Cas9 nickase-RT fusion protein and a pegRNA.
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| The Crop Biotech Update is a weekly newsletter of ISAAA, a non-for-profit organization. The CBU is distributed for free to over 23,000 subscribers worldwide to inform them about the key developments in biosciences, especially in agricultural biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10. |
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