Crop Biotech Update

CRISPR-Cas9 Helps Enhance Cassava's Disease Resistance, Drought Tolerance, and Starch Biosynthesis

March 26, 2025

A study by scientists at the Chinese Academy of Sciences has successfully used CRISPR-Cas9 to enhance cassava's disease resistance, drought tolerance, and starch content. Published in Tropical Plants, the study paves the way for more efficient cassava breeding programs.

The study identified critical genes associated with cassava mosaic disease (CMD), cassava brown streak disease (CBSD), drought stress response, and starch biosynthesis. By introducing precise edits into these genes, the researchers developed cassava plants with enhanced resistance to CMD and CBSD, two of the most destructive diseases affecting cassava crops globally.

The edited cassava plants exhibited improved drought tolerance, an essential trait in light of the growing challenges posed by climate change. The study also reports that genome-edited cassava plants showed increased starch content, which is beneficial for food security and industrial applications such as bioethanol production. The findings of this research have significant implications for global food security, particularly in developing countries where cassava is the key staple.

For more details, read the news release from the Chinese Academy of Sciences.


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