Challenges in Genome Editing of SugarcaneDecember 1, 2016
Genome editing opens unique opportunities for plant breeders to enhance crop production. The advent of RNA-guided engineered nucleases, such as CRISPR/Cas9 system holds great potential since it is simple and effective. CRISPR/Cas9 system has already been successful in several crop plants. However, the use of this technique is in its infant stage in sugarcane (Saccharum sp.).
The study of Chakravarthi Mohan from the Federal University of Sao Carlos in Brazil, reviews the use of CRISPR/Cas9 system in the improvement of sugarcane. To date, the only report on genome editing on sugarcane is about the reduction of lignin content to make it suitable for biofuel production.
One requirement for genome editing is the availability of genomic resources to design specific gRNAs and target genes with known functions. However, the sugarcane genome is not yet deciphered and the genomic resources are limited in sugarcane. Furthermore, the functions of over 10,000 sugarcane coding genes are yet to be discovered.
This study also discusses other challenges, including large genome size, polyploidy, low transformation efficiency, transgene silencing, and lack of screening techniques that may hinder genome editing in sugarcane.
For more information on this study, read the article in Frontiers in Plant Science.
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- Students Launched the First Scientific Internet Radio Station in Egypt
- Uganda PM Advocates for Biotech at NARO-MAK Conference
- Ethiopia to Commercialize Bt Cotton in Two Years
- Scientists Find Single Enzyme Controling Growth and Defense Hormones
- Australian OGTR Receives License Application for Field Trial of GM Wheat
- Researchers Reveal Characteristics of Plant Defense Compound Dhurrin
- Scientists Engineer Maize to Produce Astaxanthin
- Study Reveals the Defense Roles of Soybean GmAFS Gene Against Nematodes and Insects
Beyond Crop Biotech
- Engineers Develop Transgenic Grass that Neutralizes Toxic Pollution from Bombs, Explosives, and Munitions
From the BICs
- Filipino Students Showcase Biotech in Bag Designs
- NaCRRI Hosts ABNE Technical Advisory Team, Looks into Strengthening Biosafety Capacity
- Biotech Stakeholders Informed about New Regulation in Indonesia
- Plant Genomics and Gene Editing Congress - Europe
- Challenges in Genome Editing of Sugarcane
- Public Acceptance of Food Products from Genome-Edited Crops
Read the latest:
- Biotech Updates (May 31, 2023)
- Gene Editing Supplement (May 31, 2023)
- Gene Drive Supplement (February 22, 2023)
Subscribe to BU: