Scientists at CSIRO develop Stem Cell Safety Test
June 13, 2013| |
Scientists at the Commonwealth Scientific and Industrial Research Organization (CSIRO) have developed a test to identify unsafe stem cells. The results of their study is published in Stem Cells journal.
The research team led by Dr. Andrew Laslett took five years to come up with a new test method. They focused on comparing different types of human induced pluripotent stem cells (iPS). "The test we have developed allows us to easily identify unsafe iPS cells. Ensuring the safety of these cell lines is paramount and we hope this test will become a routine screen as part of developing safe and effective iPS-based cell therapies," explained Dr. Laslett.
The new test method uses laser technology to identify the proteins on the surface of the cells. Cells are classified based on the presence or absence of certain proteins. The unsafe cells form clusters that are easily recognizable compared with the safe cells. This test could also be used to evaluate the safety of the somatic cell nuclear transfer of human embryonic stem cells.
Read the media release at http://www.csiro.au/en/Portals/Media/CSIRO-develops-test-to-improve-stem-cell-safety.aspx. The research article is available at http://onlinelibrary.wiley.com/doi/10.1002/stem.1425/abstract.
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