Species: Chicken (Gallus gallus)

Country of 1st Author: South Korea
Year: 2018

Institute	Seoul National University, Pyeongchang-gun Gangwon-do KR
Editing Method	Other
SDN Type	SDN-1
Delivery	by combining the CRISPR-Cas9 platform and germ cell-mediated germline transmission, we generated G(0)/G(1) switch gene 2 ( G0S2) knockout (KO) chickens, and G0S2 null KO chickens showed a dramatic reduction of abdominal fat deposition without affecting other economic traits.
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
G0S2 G0/G1 Switch 2	Reduction of abdominal fat deposition and altered fatty acid composition	Quality	CRISPR Cas9 (spCas9)

References, Documents, and Links

• Disruption of G0/G1 switch gene 2 (G0S2) reduced abdominal fat deposition and altered fatty acid composition in chicken