Species: Pig (Sus scrofa domesticus)

Country of 1st Author: China
Year: 2022

Institute	Jilin University, Changchun Jilin Province CN
Editing Method	Cloned cell line
SDN Type	SDN-1
Delivery	Cells were cloned
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
PCBP1 Poly (rC)-binding protein 1	Resistance against Classical swine fever virus (CSFV)	Biotic Stress	CRISPR Cas9 (spCas9)	two sgRNAs (sg97 and sg95) were designed to target the N-terminus of the only exon

References, Documents, and Links

• Generation of PCBP1-deficient pigs using CRISPR/Cas9-mediated gene editing