Crop Biotech Update

EFSA Publishes Scientific Opinion on Four-Event Stack Maize Bt11 × MIR162 × 1507 × GA21

July 18, 2018

The European Food Safety Authority (EFSA) Panel on Genetically Modified Organisms (GMO Panel) has published the Scientific Opinion on the safety of genetically modified (GM) herbicide‐tolerant and insect‐resistant maize Bt11 × MIR162 × 1507 × GA21 (referred to hereafter as ‘four‐event stack maize') and its subcombinations independently of their origin (referred to hereafter as ‘subcombinations'). The scientific opinion is published based on the application EFSA–GMO–DE–2010–86 under Regulation (EC) No 1829/2003 from Syngenta.

The scope of application EFSA‐GMO‐DE‐2010‐86 is for the placing on the market of maize Bt11 × MIR162 × 1507 × GA21 and three subcombinations (Bt11 × MIR162 × 1507, MIR162 × 1507 × GA21 and MIR162 × 1507), independently of their origin, for food and feed uses, import and processing.

For application EFSA‐GMO‐DE‐2010‐86, the previous assessments of the four single maize events and seven subcombinations provided a basis to evaluate the four‐event stack maize and the three subcombinations included in the scope of the application. The four single maize events (Bt11, MIR162, 1507 and GA21) and seven subcombinations (Bt11 × GA21 × MIR162, Bt11 × 1507 × GA21, Bt11 × GA21, MIR162 × GA21, Bt11 × MIR162, Bt11 × 1507 and 1507 × GA21) were previously assessed by the GMO Panel and no concerns on their safety were identified.

No safety issue concerning the four single maize events was identified by the updated bioinformatic analyses nor reported by the applicant since the publication of the previous GMO Panel Scientific Opinions. Therefore, the GMO Panel considers that its previous conclusions on the safety of the single maize events remain valid.

For more details, read the scientific opinion in the EFSA Journal.