New Method to Generate Extended Data for Genome Assemblies Faster, Better, CheaperAugust 5, 2015
Scientists at The Genome Analysis Centre (TGAC) have developed a new library construction method for genome sequencing that can simultaneously construct long-range data with reduced DNA input, time, and cost. The TGAC team gained early access to a new piece of technology, the SageELF from Sage Scientific, to develop a more robust, global approach to the most accurate long range sequence data for any given sample.
Long range genetic data (long mate pair – LMP) is an invaluable source for plant, crop, and animal genetic research. Sequencing genomes requires breaking them into small manageable pieces and then working out how to put them back together. To do this, a combination of short range and long range sequence data is needed. Generating short range data is relatively straightforward, but long range data is more problematic as the quality and quantity of DNA are major factors influencing the outcome.
Darren Heavens, lead author and team leader in the Platforms & Pipelines at TGAC said, "Although producing a single high-quality size selected LMP library can be difficult, several LMP libraries are often used for larger genome sequencing projects. Our new genome analysis protocol allows concurrent construction of 12 long-range data libraries for less than twice the cost of a single library and reduces the time by 3 to 2 days."
For more information, read the news release at the TGAC website.
ISAAA shares, disseminates, and promotes science-based information to help in achieving global agricultural sustainability and development. During this time of COVID-19 pandemic, we monitor research on treatments, vaccines and keep track of the pandemic's effect on food security and agriculture. We help the public make informed decisions and actions to mitigate and recover from the impact of COVID-19. At this crucial time, we need your help. Please support our efforts today from as little as $10
See more articles:
News from Around the World
- Tanzania's Key Ag-Biotech Stakeholders Undergo SciCom Training
- GAIN Report Presents Agri-biotech Status in Morocco
- GMO Question Determines Winner of Miss Uganda 2015
- US Biotech Crops Alliance Discuss Commercial Possibilities
- USDA Scientists Develop New Technique for Lunasin Extraction
- One of 30 Top Biotech Influencers is New Dean at Tuskegee University
- Plants Release Animal-like Signals When Stressed
- NRGene Decodes Complete Genome of Emmer Wheat
- Review on Public Acceptance of Plant Biotechnology in Europe
- New Method to Generate Extended Data for Genome Assemblies Faster, Better, Cheaper
- Targeted Increase of Naturally Occurring Sugar Improves Yield of Drought Affected Corn
- Malting Barley Variety Contains a New Allele of Acid Tolerance Gene
- Rust Fungi Genes Provide Insights in Developing a Rust-Resistant Cereal Crops
- Arabidopsis NPR1 Gene Confers Broad-Spectrum Disease Resistance in Strawberry
- 3rd Plant Genomics Congress: USA
Subscribe to CBU: