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Crop Biotech Update

USDA Scientists Develop New Technique for Lunasin Extraction

August 5, 2015

Scientists at the U.S. Department of Agriculture (USDA) developed a new procedure to extract lunasin, a compound with cancer-fighting potential and anti-inflammatory activity of soybean seeds.

According to Hari Krishnan, a molecular biologist from USDA Agricultural Research Service, animal and human clinical trials of lunasin have been delayed because its extraction has been tedious, time-consuming, and expensive. However, with the new procedure that they have developed, extraction only takes less than 2 hours and yields far more lunasin and protease inhibitor concentrate than other methods, including sophisticated chromatography procedures and live cultures of GM yeast or bacteria. The actual extraction is done with a 30 percent solution of ethanol, followed by centrifuging steps and the addition of calcium chloride to further purify the concentrate.

Read the original article from USDA. The new procedure is discussed in a research article published in Food Chemistry.