Crop Biotech Update

Gene Editing Helps Identify Pathogenic Qualities of Disease-causing Bacteria in Rice

June 29, 2023

Using CRISPR, Professor Bing Yang of the University of Missouri and Donald Danforth Plant Science Center led a team in identifying problematic pathogens in specific bacteria that cause prolific infections in rice. Their investigation explains the host-pathogen relationship that can help other scientists design plants with higher disease resilience.

The team knocked out bacterial genes to study their individual functions. They then tested the genes for infectious properties. They obtained data that helped them understand which bacteria held pathogenic qualities and how the qualities were relative to infections of certain plant species. They then edited a bacterial sample to determine which genes had pathogenic qualities that infect proteins in the genome of the rice crop.

Their method was said to revolutionize the inefficient and time-consuming process of homologous recombination.

Learn more about the study in Nature and EurekAlert!


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