Simultaneous Detection of miRNAs Using Split-LAMP
November 8, 2023| |
Researchers from Singapore developed a novel Split-LAMP concept that allows the detection of two miRNAs. This cost-effective technique has a great potential for diagnosing critical illnesses.
Aberrant microRNA (miRNA) expressions are usually found in various deadly diseases, like cancer. That's why it's important to detect these miRNAs for early treatment of illnesses. Recent studies demonstrate that combinations of miRNA levels can be diagnosed more accurately compared to single miRNA levels.
Due to this knowledge, researchers from various institutions in Singapore produced a point-of-care testing (POCT) device for miRNAs. They developed a split loop-mediated isothermal amplification (LAMP) that can detect two distinct miRNAs simultaneously. The results are also easy to determine because they use a colorimetric endpoint readout that can quickly give a result after 30 minutes.
Read the journal article on Frontiers in Bioengineering and Biotechnology for more information.
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