Biotech Updates

Researchers Discover Protein that Turns Plants into Dwarfs

August 24, 2022

Plants with experimentally knocked down DWEORG1 (left) showed reduced translation efficiency as well as growth retardation and overall smaller size. Photo courtesy of Dr. Stefanie Grüttner

Researchers from Kiel University, led by Professor Frank Kempken, have characterized a novel component of plant PPR proteins previously thought to be primarily involved in RNA maturation in mitochondria. The researchers have identified a new protein that is part of the mitochondrial ribosomes and is involved in protein biosynthesis.

This new protein is part of the mitochondrial ribosomes and is involved in protein biosynthesis. Although the exact mechanism is still unknown, the researchers showed that the protein probably interferes with growth regulation. They observed that when it was artificially switched off, Arabidopsis exhibits delayed and dwarfed growth while the plant maintains full functionality.

PPR proteins are encoded by genes in the cell nucleus and transferred to the ribosomes as messenger RNA and translated into proteins. The synthesized PPR proteins are then transported to the mitochondria, where they are involved in controlling various life processes. Recently, researchers have discovered that the subgroup rPPR proteins occur in mitochondrial ribosomes. To better understand the regulation of genetic information in today's plants, the Kiel University researchers analyzed a specific common mitochondrial rPPR protein, which is encoded by the DWEORG1 gene.

The researchers found that plants with experimentally knocked down DWEORG1 showed reduced translation efficiency. However, DWEORG1 does not seem to play a fundamental role in the organism because the manipulated plants showed growth retardation only and overall smaller size, and their shape and life processes were not affected.

For more details, read the article on the Kiel University website.


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