RNAi-based GM Potato Plants Exhibit Resistance to Potato Virus Y
March 23, 2022| |
Researchers from the Agricultural Biotechnology Research Institute of Iran and partners used gene silencing techniques to develop genetically modified potato plants resistant to potato virus y (PVY), the most harmful viral disease. The results are published in Transgenic Research.
Small interfering RNAs developed from double-stranded RNAs can turn on the immune system in GM plants through the detection of virus transcripts to degrade. Thus, the researchers designed three RNAi gene constructs based on the PVY genome. Using Agrobacterium, GM plants were generated containing the designed constructs, and analyses showed confirmation of the transformation. Further analysis revealed that over 67% of the GM potato plants were resistant to PVY compared to non-GM plants, which exhibited symptoms of viral infection. Plants generated from the three constructs showed similar levels of resistance against PVY. No changes were observed in the physical characteristics of the GM potato plants when compared with the non-GM.
Read more results in Transgenic Research.
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