Isolation and Expression of Antimicrobial Camel Lactoferrin (cLf) Gene in TobaccoOctober 15, 2014
Plants have the ability to produce mammalian functional proteins with therapeutic activity, including lactoferrin, a valuable protein commonly found in milk and is important in many physiological processes such as iron transfer and immune response. Tobacco (Nicotiana tabacum) is the main plant system applied for green bioreactors since it is a leafy plant with high leaf biomass and high levels of soluble proteins.
Shiraz University's Ali Niazi, together with his team, isolated the camel's (Camelus dromedarius) lactoferrin gene (cLf) and expressed it in Nicotiana tobaccum cv. Xanthi. Analysis showed that the recombinant camel lactoferrin gene (cLf) was expressed in transgenic tobacco. Tests on protein extract from the transgenic tobacco leaves exhibited antimicrobial activity.
Lactoferrin expression in plants provides a suitable system for large-scale production of this protein. Furthermore, it has been demonstrated that lactoferrin expression in plants confers resistance to plant diseases.
For further information on the study, read the full article here: http://www.pomics.com/niazi_7_5_2014_298_307.pdf
Biotech Updates is a weekly newsletter of ISAAA, a not-for-profit organization. It is distributed for free to over 22,000 subscribers worldwide to inform them about the key developments in biosciences, especially in biotechnology. Your support will help us in our mission to feed the world with knowledge. You can help by donating as little as $10.
See more articles:
News from Around the World
- ABIC 2014 Speakers Discuss Global Food Security, Agri Innovation Strategies, and Leadership
- Borlaug Dialogue Tackles Feeding 9B People in 2050
- New Imaging System Helps Plant Geneticists Improve Crops
- Anti-GMO Consumers Don't Know What GMOs Are, Show Finds
- New Gene Discovery to Enhance Quality of Cereal and Bioenergy Crops
- Experts Reveal Challenges in Communicating Agri-biotech
- RT Canola Available in Australia Next Year
- Researchers Sequence 360 Tomato Varieties to Produce Map of Evolution
- Scientists Analyze Antioxidant Characteristics of Wild Tomatoes
- AtSTO1 Overexpression Leads to Enhanced Salt Tolerance in Poplar
- NF-YC from Bermuda Grass to Improve Drought and Salinity in Rice
- Isolation and Expression of Antimicrobial Camel Lactoferrin (cLf) Gene in Tobacco
Beyond Crop Biotech
- Bio-engineered Yogurt to Replace Colonoscopy in the Future
- Developing a Bacterial Cold Water Resistant Trout
- Next Generation Genomics and Integrated Breeding Conference
Read the latest:
- Biotech Updates (February 1, 2023)
- Genome Editing Supplement (January 18, 2023)
- Gene Drive Supplement (January 25, 2023)
Subscribe to BU: