Species: Pig (Sus scrofa domesticus)

Country of 1st Author: China
Year: 2023

Institute	Jilin University, Changchun Jilin Province CN
Editing Method	Cloned cell line
SDN Type	SDN-2
Delivery	The three plasmids were cotransfected into cells under optimal conditions by electroporation.
Foreign DNA	Yes
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
pAPN	Resistance against enteric coronaviruses	Biotic Stress	CRISPR Cas9 (spCas9)	APN-chimeric gene-edited pigs, residues 717 to 839 were replaced with homologous murine APN

References, Documents, and Links

• Generation of APN-chimeric gene-edited pigs by CRISPR/Cas9-mediated knock-in strategy