Crop Biotech Update

Gene Editing Improves Fruit Quality of Tomatoes

April 16, 2025

Researchers from Zheijang University and Northwest A&F University used gene editing to manipulate the light systemic signal HY5 and improve the fruit quality of tomatoes. The findings of the study are published in Advanced Science.

Tomato fruit ripening involves major metabolic shifts influenced by environmental factors. Aside from photosynthesis, light also plays a critical role in regulating plant growth, development, and the quality of produce. In this study, the researchers found that the HY5 protein peaks during the breaker stage of fruit maturity. The results of the study showed that the knockout of HY5 delays carotenoid synthesis and sucrose conversion, while its overexpression promotes fruit ripening.

Further analysis revealed that HY5 directly activates key carotenoid synthesis genes and sucrose metabolism genes. Grafting experiments also showed that HY5 moves from leaves to fruits, acting as a systemic signal that supports ripening. The study also found that exposure to red or blue LED lights at night improved fruit quality, offering practical uses for light-based treatments in agriculture.

For more information, read the study from Advanced Science.


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