Biotech Updates

CSHL Scientists Discover Master Switch for Plant Growth

September 24, 2025

A thin section of a maize ear at a very early stage of development (about 3 millimeters long). Each color represents the expression of a different gene in stem cells and associated cells.

In a new study, Cold Spring Harbor Laboratory plant biologists have successfully mapped the genes that regulate plant stem cells in maize and the model plant Arabidopsis. This research, which also uncovered new regulators, could be foundational for breeding more productive and resilient crops in the future.

Now, for the first time, Cold Spring Harbor Laboratory (CSHL) plant biologists have mapped two known stem cell regulators across thousands of maize and Arabidopsis shoot cells. Their research also uncovered new stem cell regulators in both species and linked some to size variations in maize.

By using single-cell RNA sequencing, CSHL researchers led by David Jackson mapped key plant stem cell regulators in maize and Arabidopsis. Single-cell RNA sequencing allowed the team to recover about 5,000 CLAVATA3 and 1,000 WUSCHEL-expressing cells. This technique allowed them to identify new genes linked to plant productivity, providing valuable data that could help breeders develop more resilient and higher-yielding crops.

For more details, read the news article on the CSHL website.


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