Biotech Updates

Scientists Develop DNA Origami

April 10, 2014

Scientists from the University of Udine, Italy successfully modelled a prototype for a DNA origami nanorobot that can potentially deliver biological activators in living organisms. The nanorobot is cylindrical in shape, with a diameter of 14nm, length of 48nm, and has a switchable flap. According to the researchers, the robot is able to respond to an outside stimulus and reacts by a physical switch from a disarmed to an armed configuration able to deliver a cellular compatible message. To create such a nanorobot, a single stranded DNA molecule is folded into the shape, and thus the technique was called "DNA origami".

Nanobiotechnology is a relatively new discipline that combines nanotechnology and biotechnology. DNA origami is still in the research or testing phase. It has many potential applications such as drug delivery systems and controlling the functions of molecules. According to Guiseppe Firrao, leader of the study, their technology will be useful in agriculture, particularly for development of techniques for pathogen control. At present, their main objective is to develop nanorobots that can respond to molecular signals.

Read more at http://www.european-biotechnology-news.com/news/news/2014-02/dna-origami-with-a-flap.html and http://onlinelibrary.wiley.com/enhanced/doi/10.1002/smll.201400245/.