Developer:
Dow AgroSciences LLC

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Lepidopteran insect resistance , Antibiotic resistance , 2,4-D herbicide tolerance

Commercial Trait:
(Stacked)  Herbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced	Gene Source	Product	Function
cry1Ac	Bacillus thuringiensis subsp. Kurstaki strain HD73	Cry1Ac delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
vip3A(a)	Bacillus thuringiensis strain AB88	VIP3A vegetative insecticidal protein	confers resistance to feeding damage caused by lepidopteran insects by selectively damaging their midgut lining
cry1F	Bacillus thuringiensis var. aizawai	Cry1F delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
aph4 (hpt)  *	Escherichia coli	hygromycin-B phosphotransferase (hph) enzyme	allows selection for resistance to the antibiotic hygromycin B
cp4 epsps (aroA:CP4)	Agrobacterium tumefaciens strain CP4	herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme	decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide
pat	Streptomyces viridochromogenes	phosphinothricin N-acetyltransferase (PAT) enzyme	eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation
aad-12	Delftia acidovorans	aryloxyalkanoate di-oxygenase 12 (AAD-12) protein	catalyzes the side chain degradation of 2,4-D herbicide

 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country	Food direct use or processing	Feed direct use or processing	Cultivation domestic or non-domestic use
Japan
Mexico
South Korea

 

Regulatory and Biosafety Information

• CIBIOGEM - Mexico
• FAO GM Foods Platform (Mexico)
• Japan Biosafety Clearing House
• Korea Biosafety Clearing House