Species: Goat (Capra hircus)

Country of 1st Author: China
Year: 2017

Institute	Northwest A&F University Yangling 712100, Shaanxi CN
Editing Method	Embryo edit
SDN Type	SDN-1
Delivery	In the present study we report that by co-injecting synthesised RNAs and single-stranded oligo deoxynucleotide (ssODN) donor sequences into goat zygotes, we successfully introduced defined point mutations resulting in single amino acid substitutions in the proteins as expected.
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
GDF9 Growth Differentiation Factor 9	Increase in litter size	Reproduction	CRISPR Cas9 (spCas9)

References, Documents, and Links

• Efficient generation of goats with defined point mutation (I397V) in GDF9 through CRISPR/Cas9