Species: Cattle (Bos taurus)

Country of 1st Author: United States
Year: 2021

Institute	University of California, Davis US
Editing Method	Embryo edit
SDN Type	SDN-3
Delivery	the repair template was provided as a template, and everything was microinjected in at 6 hpi - we transferred only green embryos resulting in a knocked in male bull calf - Cosmo
Foreign DNA	Yes
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
SRY Sex Determining Region Y	Sex reversal of XY males into females	Reproduction	CRISPR Cas9 (spCas9)	Targeted safe harbor locus (H11) on chromosome 17 with SRY-GFP construct

References, Documents, and Links