Species: Pig (Sus scrofa domesticus)

Country of 1st Author: China
Year: 2017

Institute	Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University Shenzhen 518035 CN
Editing Method	Cloned cell line
SDN Type	SDN-1
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
GGTA1 α-1,3-galactosyltransferase	Hypoallergenic meat	Hypoallergenic	CRISPR Cas9 (spCas9)
CMAH Cytidine monophosphate-N-acetylneuraminic acid hydroxylase	Resistance against porcine epidemic diarrhoea virus (PEDV)	Biotic Stress	CRISPR Cas9 (spCas9)

References, Documents, and Links

• Production of a1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning