Species: Pig (Sus scrofa domesticus)

Country of 1st Author: United Kingdom
Year: 2016

Breed Strain	Large White
Institute	University of Edinburgh Edinburgh, EH25 9RG UK
Editing Method	Embryo edit
SDN Type	SDN-2
Delivery	Embryos were subjected to a single 2–5pl cytoplasmic injection of the pVAX single mRNAs at 2 ng/ul or 4 ng/µ l with ssODN or plasmid template respectively.
Foreign DNA	Yes
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
RELA	Resistance against African Swine Fever	Biotic Stress	ZFN	A 96-mer ssODN was designed spanning the target site of the ZFN containing two base changes encoding the T448A conversion

References, Documents, and Links

• Mammalian interspecies substitution of immune modulatory alleles by genome editing