Species: Cattle (Bos taurus)

Country of Determination: Argentina
Year: 2020

Breed Strain	Holstein
Commercial Name	Celtic Pc polled/SLICK Holstein
Developer	Acceligen Inc. Eagan, MN US
Editing Method	Other
SDN Type	SDN-1
Foreign DNA	No
Undergone Regulatory Process	Yes

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
PRLR Prolactin Receptor	This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.	Abiotic Stress	CRISPR Cas9 (spCas9)
Pc POLLED Pc POLLED		Other	CRISPR Cas9 (spCas9)

Regulatory Documents and Links