Species: Nile tilapia (Oreochromis niloticus)

Country of 1st Author: China
Year: 2015

Institute	Southwest University 400715 Chongqing CN
Editing Method	Embryo edit
SDN Type	SDN-1
Delivery	gRNA or Cas9 mRNA injeccted into fertilized eggs
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
aldh1a2 Aldehyde dehydrogenase family 1 member A2	Specifically germ cell entry into meiosis	Reproduction	CRISPR Cas9 (spCas9)
cyp26a1 cytochrome P450, family 26, subfamily A, polypeptide 1	Specifically germ cell entry into meiosis	Reproduction	CRISPR Cas9 (spCas9)

References, Documents, and Links

• Retinoic acid homeostasis through aldh1a2 and cyp26a1 mediates meiotic entry in Nile tilapia (Oreochromis niloticus)