Biotech Updates

Major Breakthrough in Understanding Plant Disease Resistance

April 23, 2014

Researchers at The Sainsbury Laboratory (TSL) in Norwich, together with structural biologist Bostjan Kobe in Brisbane, have made a major advance in understanding plant disease resistance. TSL Professor Jonathan Jones said that they are aware that proteins called RRS1 and RPS4 help recognize specific molecules from pathogenic bacteria, and then use this recognition as a cue to activate defense. How this unique dual-protein recognition system operates has remained unknown and is the focus of investigations in Professor Jones' laboratory.

According to Professor Jones, the proteins intimately associate, and their research part of that association at atomic detail. They also found that mutations which disturb this association disrupt its function and leave plants more vulnerable to attack.

For more about this research, read the TSL news release available at http://www.tsl.ac.uk/plant-disease-resistance.html. The results of the research is published in the April 18th edition of Science Magazine, available at http://www.sciencemag.org/content/344/6181/299.full.