Biotech Updates

Researchers Develop Cold-Resistant Tomato Without Compromising Growth

November 12, 2025

Increased levels of glycosylated sterols in tomatoes improve cold tolerance by stabilizing cell membranes and activating hormonal signalling pathways. Photo Source: CRAG

The tomato plant is highly susceptible to cold stress, with temperatures below 12°C severely impairing its growth and development. This sensitivity leads to crop failure and food waste, particularly in regions with unpredictable weather. To solve this challenge, researchers at the University of Barcelona and the Centre for Research in Agricultural Genomics (CRAG) developed a new cold-resistant tomato variety that maintains robust growth without compromise.

The researchers discovered that increasing glycosylated sterol (GS) levels in tomato improves cold tolerance by stabilizing cell membranes and activating hormonal signaling pathways. Unlike most plants, where GS are minor components, these molecules are predominant in the Solanaceae family. By increasing GS levels—specifically by overexpressing the SlSGT2 enzyme—the scientists found that these molecules act as crucial cold sensors. They not only stabilize the plasma membrane but also activate a complete protective molecular response, effectively "pre-conditioning" the plant.

This preconditioned state triggers an early defense mechanism that includes the activation of hormonal signaling pathways, particularly those involving jasmonates, and the upregulation of antioxidant enzymes and defense genes. The result is a plant prepared to withstand the damaging effects of cold stress, opening new biotechnological avenues for agriculture. This innovation promises to increase yields, reduce pre-harvest food waste caused by cold snaps, and enable more sustainable cultivation practices by potentially lowering the need for energy-intensive greenhouse heating.

For more details, read the article in CRAG News.


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