Researchers Construct Soybean's Pan-3D Genome

A research group at the Chinese Academy of Sciences (CAS) led by Prof. TIAN Zhixi from the Institute of Genetics and Developmental Biology has constructed a pan-3D genome of soybean, revealing the internal relationships among soybean genome, 3D genome, and gene expression.

Published in Genome Biology, the study obtained high-quality 3D genome data by performing high-throughput chromatin conformation capture experiments on 27 soybean germplasm materials that were de novo assembled in a previous study.

The research team also explored the selection process of the 3D genome in wild soybean, landraces, and cultivars during domestication and improvement and found that 3D genome selection mainly occurred during domestication, rather than during improvement. This selection reshaped gene regulation and led to changes in soybean gene expression.

For more details, read the article in the CAS Newsroom.