High-Def Genome Profiling Aids Marker Discovery
May 18, 2007| |
Genetic maps allow the genetic position of genes and markers associated with phenotypic traits to be identified. With the recent advances in microarray technology, high definition maps are now possible. These maps will allow the precise pinpointing of genes of interest.
In a review paper, researchers in Syngenta discussed how single feature polymorphisms (SFPs) from microarray analysis can help in genetic mapping and in the identification of genetic variation. SFPs are DNA hybridization polymorphic markers detected by a high-density microarray.
The SFPs have emerged as attractive alternatives to single nucleotide polymorphisms (SNPs) for high-definition genetic mapping. The researchers foresee that they will play a profound role in steps towards high definition genetic discovery and genomic analyses of crop traits in the near future.
The review paper in the journal Trends in Plant Science is accessible online at http://dx.doi.org/10.1016/j.tplants.2007.03.013.
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